Microscopy is key in the research, formulation and manufacturing stages of pharmaceutical product development. Both optical and scanning electron microscopy (SEM) are often used to optimize particle size, morphology and roughness of pharmaceutical materials. Understanding size distribution and morphology of pharmaceutical particles either containing active pharmaceutical ingredients (API) or excipients is critical for optimizing both the compounding process and product solubility.
Particle size distribution, morphology and chemical composition
SEM imaging and EDS analysis applied to pharmaceutical QA/QC
Use SEM/EDS to determine the composition of foreign particles extracted from injectable drug compounds.
Deformulation, also referred to as reverse engineering, for the pharmaceutical industry
Characterize pharmaceutical surfaces and coatings with 3D profilometry, AFM, SEM and elemental analysis
Case studies using the Phenom SEM for pharmaceutical and medical research